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ROS Enhances CXCR4-mediated Functions through Inactivation of PTEN in Prostate Cancer Cells

Inactivation of the tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is heavily implicated in the tumorigenesis of prostate cancer. Conversely, the upregulation of the chemokine (CXC) receptor 4 (CXCR4) is associated with prostate cancer progression and metastasis. Stu...

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Autors principals: Chetram, Mahandranauth A., Don-Salu-Hewage, Ayesha S., Hinton, Cimona V.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163383/
https://ncbi.nlm.nih.gov/pubmed/21627959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.05.074
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