Hypoxia-inducible factor-1 α/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling

BACKGROUND: Human immunodeficiency virus (HIV) infected patients are at increased risk for the development of pulmonary arterial hypertension (PAH). Recent reports have demonstrated that HIV associated viral proteins induce reactive oxygen species (ROS) with resultant endothelial cell dysfunction an...

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Detalhes bibliográficos
Main Authors: Mermis, Joel, Gu, Haihua, Xue, Bing, Li, Fang, Tawfik, Ossama, Buch, Shilpa, Bartolome, Sonja, O'Brien-Ladner, Amy, Dhillon, Navneet K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163194/
https://ncbi.nlm.nih.gov/pubmed/21819559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-12-103
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