TLR9-induced interferon β is associated with protection from gammaherpesvirus-induced exacerbation of lung fibrosis

BACKGROUND: We have shown previously that murine gammaherpesvirus 68 (γHV68) infection exacerbates established pulmonary fibrosis. Because Toll-like receptor (TLR)-9 may be important in controlling the immune response to γHV68 infection, we examined how TLR-9 signaling effects exacerbation of fibros...

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Main Authors: Luckhardt, Tracy R, Coomes, Stephanie M, Trujillo, Glenda, Stoolman, Joshua S, Vannella, Kevin M, Bhan, Urvashi, Wilke, Carol A, Moore, Thomas A, Toews, Galen B, Hogaboam, Cory, Moore, Bethany B
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163187/
https://ncbi.nlm.nih.gov/pubmed/21810214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-4-18
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