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Development of a peptide-drug conjugate for prostate cancer therapy

TGX-221 is a highly potent phosphoinositide 3-kinases β (PI3Kβ) inhibitor that holds great promise as a novel chemotherapeutic agent to treat prostate cancer. However, poor solubility and lack of targetability limit its therapeutic applications. The objective of this present study is to develop a pe...

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Hlavní autoři: Tai, Wanyi, Shukla, Ravi S., Qin, Bin, Li, Benyi, Cheng, Kun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163154/
https://ncbi.nlm.nih.gov/pubmed/21510670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200007b
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