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Molecular Dynamics Simulations Reveal the Protective Role of Cholesterol in Beta Amyloid Protein-Induced Membrane Disruptions in Neuronal Membrane Mimics

Interactions of beta-amyloid (Aβ) peptides with neuronal membranes have been associated with the pathogenesis of Alzheimer’s disease, however the molecular details remain unclear. We used atomistic molecular dynamics simulations to study the interactions of Aβ(40) and Aβ(42) with model neuronal memb...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Qiu, Liming, Buie, Creighton, Reay, Andrew, Vaughn, Mark W., Cheng, Kwan Hon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163122/
https://ncbi.nlm.nih.gov/pubmed/21740063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp2012842
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