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Time-reversal Techniques in Ultrasound-assisted Convection-enhanced Drug Delivery to the Brain: Technology Development and In Vivo Evaluation

We describe a drug delivery method that combines Time-Reversal Acoustics (TRA) with Convection-Enhanced Delivery (CED) to improve the delivery of therapeutics to the interstitium of the brain. The Ultrasound-assisted CED approach (UCED) circumvents the blood-brain barrier by infusing compounds throu...

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Detalhes bibliográficos
Main Authors: Lewis, George K., Guarino, Sabrina, Gandhi, Gaurav, Filinger, Laurent, Olbricht, Willam L., Sarvazyan, Armen
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163071/
https://ncbi.nlm.nih.gov/pubmed/21881622
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