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Total Synthesis of (±)-Phomactin A. Lessons Learned from Respecting a Challenging Structural Topology

[Image: see text] Our struggles and ultimate success in achieving a total synthesis of phomactin A are described. Our strategy features an intramolecular oxa-[3 + 3] annulation to construct its unique ABD-tricyclic manifold. Although the synthesis would constitute a distinctly new approach with the...

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Detaylı Bibliyografya
Asıl Yazarlar: Buchanan, Grant S., Cole, Kevin P., Tang, Yu, Hsung, Richard P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163054/
https://ncbi.nlm.nih.gov/pubmed/21819039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo200936r
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