Phosphodiesterase Type 4D Gene Polymorphism: Association with the Response to Short-Acting Bronchodilators in Paediatric Asthma Patients

Short-acting b2-adrenergic receptor agonists are commonly used bronchodilators for symptom relief in asthmatics. The aim of this study was to test whether genetic variants in PDE4D gene, a key regulator of b2-adrenoceptor-induced cAMP turnover in airway smooth muscle cells, affect the response to sh...

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Detalhes bibliográficos
Main Authors: Labuda, Malgorzata, Laberge, Sophie, Brière, Julie, Bérubé, Denis, Beaulieu, Patrick, Pastinen, Tomi, Krajinovic, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163044/
https://ncbi.nlm.nih.gov/pubmed/21876611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/301695
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