A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder

AIMS: To assess and compare the mechanisms of central nervous system (CNS) penetration of antimuscarinic overactive bladder (OAB) agents. METHODS: Physical properties were computed or compiled from the literature. Rats were administered 5-hydroxymethyl tolterodine (HMT), darifenacin, oxybutynin, sol...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Callegari, Ernesto, Malhotra, Bimal, Bungay, Peter J, Webster, Rob, Fenner, Katherine S, Kempshall, Sarah, LaPerle, Jennifer L, Michel, Martin C, Kay, Gary G
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Science Inc 2011
נושאים:
Uropharmacology Themed Section
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162653/
https://ncbi.nlm.nih.gov/pubmed/21392072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.03961.x
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