Efficient Differentiation of Embryonic Stem Cells into Hepatic Cells In Vitro Using a Feeder-Free Basement Membrane Substratum

The endoderm-inducing effect of the mesoderm-derived supportive cell line M15 on embryonic stem (ES) cells is partly mediated through the extracellular matrix, of which laminin α5 is a crucial component. Mouse ES or induced pluripotent stem cells cultured on a synthesized basement membrane (sBM) sub...

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Библиографические подробности
Главные авторы: Shiraki, Nobuaki, Yamazoe, Taiji, Qin, Zeng, Ohgomori, Keiko, Mochitate, Katsumi, Kume, Kazuhiko, Kume, Shoen
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162614/
https://ncbi.nlm.nih.gov/pubmed/21887386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024228
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