Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer

BACKGROUND: Epigenetic control is essential for maintenance of tissue hierarchy and correct differentiation. In cancer, this hierarchical structure is altered and epigenetic control deregulated, but the relationship between these two phenomena is still unclear. CD133 is a marker for adult stem cells...

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Autors principals: Pellacani, Davide, Packer, Richard J, Frame, Fiona M, Oldridge, Emma E, Berry, Paul A, Labarthe, Marie-Christine, Stower, Michael J, Simms, Matthew S, Collins, Anne T, Maitland, Norman J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162587/
https://ncbi.nlm.nih.gov/pubmed/21801380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-94
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