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Molecular Basis of Actin Nucleation Factor Cooperativity: CRYSTAL STRUCTURE OF THE SPIR-1 KINASE NON-CATALYTIC C-LOBE DOMAIN (KIND)·FORMIN-2 FORMIN SPIR INTERACTION MOTIF (FSI) COMPLEX
The distinct actin nucleation factors of the Spir and formin subgroup families cooperate in actin nucleation. The Spir/formin cooperativity has been identified to direct two essential steps in mammalian oocyte maturation, the asymmetric spindle positioning and polar body extrusion during meiosis. Un...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162434/ https://ncbi.nlm.nih.gov/pubmed/21705804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.257782 |
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