IL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells

IL-7 is an important cytokine for lymphocyte differentiation. Similar to what occurs in vivo, human CD19(+) cells developing in human/murine xenogeneic cultures show differential expression of the IL-7 receptor α (IL-7Rα) chain (CD127). We now describe the relationship between CD127 expression/signa...

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Main Authors: Nodland, Sonja E., Berkowska, Magdalena A., Bajer, Anna A., Shah, Nisha, de Ridder, Dick, van Dongen, Jacques J. M., LeBien, Tucker W., van Zelm, Menno C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162350/
https://ncbi.nlm.nih.gov/pubmed/21680796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-302513
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