Correlating SHAPE signatures with three-dimensional RNA structures

Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE) is a facile technique for quantitative analysis of RNA secondary structure. In general, low SHAPE signal values indicate Watson-Crick base-pairing, and high values indicate positions that are single-stranded within the RNA structur...

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Huvudupphovsmän: Bindewald, Eckart, Wendeler, Michaela, Legiewicz, Michal, Bona, Marion K., Wang, Yi, Pritt, Mark J., Le Grice, Stuart F.J., Shapiro, Bruce A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162334/
https://ncbi.nlm.nih.gov/pubmed/21752927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2640111
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