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Maternal Obesity during Gestation Impairs Fatty Acid Oxidation and Mitochondrial SIRT3 Expression in Rat Offspring at Weaning

In utero exposure to maternal obesity increases the offspring's risk of obesity in later life. We have also previously reported that offspring of obese rat dams develop hepatic steatosis, mild hyperinsulinemia, and a lipogenic gene signature in the liver at postnatal day (PND)21. In the current...

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Detalhes bibliográficos
Main Authors: Borengasser, Sarah J., Lau, Franchesca, Kang, Ping, Blackburn, Michael L., Ronis, Martin J. J., Badger, Thomas M., Shankar, Kartik
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162035/
https://ncbi.nlm.nih.gov/pubmed/21901160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024068
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