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Computational Study of the Human Dystrophin Repeats: Interaction Properties and Molecular Dynamics

Dystrophin is a large protein involved in the rare genetic disease Duchenne muscular dystrophy (DMD). It functions as a mechanical linker between the cytoskeleton and the sarcolemma, and is able to resist shear stresses during muscle activity. In all, 75% of the dystrophin molecule consists of a lar...

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Bibliografiske detaljer
Main Authors: Legrand, Baptiste, Giudice, Emmanuel, Nicolas, Aurélie, Delalande, Olivier, Le Rumeur, Elisabeth
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162007/
https://ncbi.nlm.nih.gov/pubmed/21901138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023819
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