SMURF1 Amplification Promotes Invasiveness in Pancreatic Cancer

Pancreatic cancer is a deadly disease, and new therapeutic targets are urgently needed. We previously identified DNA amplification at 7q21-q22 in pancreatic cancer cell lines. Now, by high-resolution genomic profiling of human pancreatic cancer cell lines and human tumors (engrafted in immunodeficie...

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Main Authors: Kwei, Kevin A., Shain, A. Hunter, Bair, Ryan, Montgomery, Kelli, Karikari, Collins A., van de Rijn, Matt, Hidalgo, Manuel, Maitra, Anirban, Bashyam, Murali D., Pollack, Jonathan R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161761/
https://ncbi.nlm.nih.gov/pubmed/21887346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023924
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