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Stable folding core in the folding transition state of an α-helical integral membrane protein
Defining the structural features of a transition state is important in understanding a folding reaction. Here, we use Φ-value and double mutant analyses to probe the folding transition state of the membrane protein bacteriorhodopsin. We focus on the final C-terminal helix, helix G, of this seven tra...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3161581/ https://ncbi.nlm.nih.gov/pubmed/21831834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012594108 |
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