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Stable folding core in the folding transition state of an α-helical integral membrane protein

Defining the structural features of a transition state is important in understanding a folding reaction. Here, we use Φ-value and double mutant analyses to probe the folding transition state of the membrane protein bacteriorhodopsin. We focus on the final C-terminal helix, helix G, of this seven tra...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Curnow, Paul, Di Bartolo, Natalie D., Moreton, Kathleen M., Ajoje, Oluseye O., Saggese, Nicholas P., Booth, Paula J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161581/
https://ncbi.nlm.nih.gov/pubmed/21831834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012594108
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