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AN OPTIMIZED SMALL MOLECULE INHIBITOR COCKTAIL SUPPORTS LONG-TERM MAINTENANCE OF HUMAN EMBRYONIC STEM CELLS

A major challenge in stem-cell mediated regenerative medicine is the development of defined culture systems for the maintenance of clinical-grade human embryonic stem (hES) cells. Using a feedback system control scheme, we identified a unique combination of three small molecule inhibitors that enabl...

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Detalhes bibliográficos
Principais autores: Tsutsui, Hideaki, Valamehr, Bahram, Hindoyan, Antreas, Qiao, Rong, Ding, Xiangting, Guo, Shuling, Witte, Owen N., Liu, Xin, Ho, Chih-Ming, Wu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161511/
https://ncbi.nlm.nih.gov/pubmed/21266967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1165
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