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Improvements in proteomic metrics of low abundance proteins through proteome equalization using ProteoMiner prior to MudPIT
Ideally shotgun proteomics would facilitate the identification of an entire proteome with 100% protein sequence coverage. In reality, the large dynamic range and complexity of cellular proteomes results in oversampling of abundant proteins, while peptides from low abundance proteins are undersampled...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3161494/ https://ncbi.nlm.nih.gov/pubmed/21702434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200304u |
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