LIF, a Novel STAT5-Regulated Gene, Is Aberrantly Expressed in Myeloproliferative Neoplasms

A search for genes potentially regulated by STAT5 identified leukemia inhibitory factor (LIF) as a good candidate. Using various experimental approaches, we have validated LIF as a direct transcriptional target of STAT5 in myeloid cell lines: STAT5 binds to LIF promoter, and LIF expression is increa...

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Bibliographic Details
Main Authors: Salas, Elisa M., García-Barchino, María J., Labiano, Sara, Shugay, Mikhail, Pérez-Encinas, Manuel, Quinteiro, Celsa, García-Delgado, Marina, Vizmanos, José L., Novo, Francisco J.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2011
Subjects:
Short Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161423/
https://ncbi.nlm.nih.gov/pubmed/21901172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911420139
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