Ranpirnase Interferes with NF-κB Pathway and MMP9 Activity, Inhibiting Malignant Mesothelioma Cell Invasiveness and Xenograft Growth

The ribonuclease ranpirnase (Onconase) has been used empirically to treat malignant mesothelioma (MM) patients, and some of them had prolonged survivals. The aim of this study was to investigate the mechanisms of the therapeutic function of ranpirnase in MM cells. The effects of ranpirnase were stud...

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Bibliografski detalji
Glavni autori: Nasu, Masaki, Carbone, Michele, Gaudino, Giovanni, Ly, Bevan H., Bertino, Pietro, Shimizu, David, Morris, Paul, Pass, Harvey I., Yang, Haining
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2011
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161417/
https://ncbi.nlm.nih.gov/pubmed/21901170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911412375
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