ARG098, a novel anti-human Fas antibody, suppresses synovial hyperplasia and prevents cartilage destruction in a severe combined immunodeficient-HuRAg mouse model

BACKGROUND: The anti-human Fas/APO-1/CD95 (Fas) mouse/human chimeric monoclonal IgM antibody ARG098 (ARG098) targets the human Fas molecule. The cytotoxic effects of ARG098 on cells isolated from RA patients, on normal cells in vitro, and on RA synovial tissue and cartilage in vivo using implanted r...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Odani-Kawabata, Noriko, Takai-Imamura, Miwa, Katsuta, Osamu, Nakamura, Hiroshi, Nishioka, Kusuki, Funahashi, Keiko, Matsubara, Tsukasa, Sasano, Minoru, Aono, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161399/
https://ncbi.nlm.nih.gov/pubmed/20875116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-11-221
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados