The Unconventional Role of Acid Sphingomyelinase in Regulation of Retinal Microangiopathy in Diabetic Human and Animal Models

OBJECTIVE: Acid sphingomyelinase (ASM) is an important early responder in inflammatory cytokine signaling. The role of ASM in retinal vascular inflammation and vessel loss associated with diabetic retinopathy is not known and represents the goal of this study. RESEARCH DESIGN AND METHODS: Protein an...

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Detalhes bibliográficos
Main Authors: Opreanu, Madalina, Tikhonenko, Maria, Bozack, Svetlana, Lydic, Todd A., Reid, Gavin E., McSorley, Kelly M., Sochacki, Andrew, Perez, Gloria I., Esselman, Walter J., Kern, Timothy, Kolesnick, Richard, Grant, Maria B., Busik, Julia V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161322/
https://ncbi.nlm.nih.gov/pubmed/21771974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0550
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