Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant: A 14-Cohort Meta-analysis

OBJECTIVE: Many genetic variants have been associated with glucose homeostasis and type 2 diabetes in genome-wide association studies. Zinc is an essential micronutrient that is important for β-cell function and glucose homeostasis. We tested the hypothesis that zinc intake could influence the gluco...

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Detalhes bibliográficos
Main Authors: Kanoni, Stavroula, Nettleton, Jennifer A., Hivert, Marie-France, Ye, Zheng, van Rooij, Frank J.A., Shungin, Dmitry, Sonestedt, Emily, Ngwa, Julius S., Wojczynski, Mary K., Lemaitre, Rozenn N., Gustafsson, Stefan, Anderson, Jennifer S., Tanaka, Toshiko, Hindy, George, Saylor, Georgia, Renstrom, Frida, Bennett, Amanda J., van Duijn, Cornelia M., Florez, Jose C., Fox, Caroline S., Hofman, Albert, Hoogeveen, Ron C., Houston, Denise K., Hu, Frank B., Jacques, Paul F., Johansson, Ingegerd, Lind, Lars, Liu, Yongmei, McKeown, Nicola, Ordovas, Jose, Pankow, James S., Sijbrands, Eric J.G., Syvänen, Ann-Christine, Uitterlinden, André G., Yannakoulia, Mary, Zillikens, M. Carola, Wareham, Nick J., Prokopenko, Inga, Bandinelli, Stefania, Forouhi, Nita G., Cupples, L. Adrienne, Loos, Ruth J., Hallmans, Goran, Dupuis, Josée, Langenberg, Claudia, Ferrucci, Luigi, Kritchevsky, Stephen B., McCarthy, Mark I., Ingelsson, Erik, Borecki, Ingrid B., Witteman, Jacqueline C.M., Orho-Melander, Marju, Siscovick, David S., Meigs, James B., Franks, Paul W., Dedoussis, George V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161318/
https://ncbi.nlm.nih.gov/pubmed/21810599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0176
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