Efficacy and Safety of Antioxidant Treatment With α-Lipoic Acid Over 4 Years in Diabetic Polyneuropathy: The NATHAN 1 trial

OBJECTIVE: To evaluate the efficacy and safety of α-lipoic acid (ALA) over 4 years in mild-to-moderate diabetic distal symmetric sensorimotor polyneuropathy (DSPN). RESEARCH DESIGN AND METHODS: In a multicenter randomized double-blind parallel-group trial, 460 diabetic patients with mild-to-moderate...

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Main Authors: Ziegler, Dan, Low, Phillip A., Litchy, William J., Boulton, Andrew J.M., Vinik, Aaron I., Freeman, Roy, Samigullin, Rustem, Tritschler, Hans, Munzel, Ullrich, Maus, Joachim, Schütte, Klemens, Dyck, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161301/
https://ncbi.nlm.nih.gov/pubmed/21775755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-0503
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