Declining β-Cell Function Relative to Insulin Sensitivity With Escalating OGTT 2-h Glucose Concentrations in the Nondiabetic Through the Diabetic Range in Overweight Youth

OBJECTIVE: Overweight in youth is associated with the risk of developing type 2 diabetes. We hypothesized that β-cell function relative to insulin sensitivity decreases with increasing 2-h glucose levels based on an oral glucose tolerance test (OGTT) in overweight youth. RESEARCH DESIGN AND METHODS:...

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Main Authors: Burns, Stephen F., Bacha, Fida, Lee, So Jung, Tfayli, Hala, Gungor, Neslihan, Arslanian, Silva A.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2011
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161262/
https://ncbi.nlm.nih.gov/pubmed/21750275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-0423
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