Pharmacogenetics of glucocorticoid replacement could optimize the treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency

INTRODUCTION: 21-hydroxylase deficiency is an autosomal recessive disorder that causes glucocorticoid deficiency and increased androgen production. Treatment is based on glucocorticoid replacement; however, interindividual variability in the glucocorticoid dose required to achieve adequate hormonal...

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Hlavní autoři: Moreira, Ricardo P. P., Jorge, Alexander A. L., Gomes, Larissa G., Kaupert, Laura C., Filho, João Massud, Mendonca, Berenice B., Bachega, Tânia A. S. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2011
Témata:
Clinical Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161212/
https://ncbi.nlm.nih.gov/pubmed/21915484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1807-59322011000800009
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