Ginkgolide A-Gold Nanoparticles Inhibit Vascular Smooth Muscle Proliferation and Migration in Vitro and Reduce Neointimal Hyperplasia in a Mouse Model

BACKGROUND: Neointimal formation is mediated by phenotypic changes in vascular smooth muscle cells (SMC) and is an important mediator of restenosis following arterial reconstruction. We conjugated antioxidant Ginkgolide A (GA) to gold nanoparticles (GNP) to determine the effect of GA delivery on neo...

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Detalhes bibliográficos
Main Authors: Weakley, Sarah M., Wang, Xinwen, Mu, Hong, Lü, Jianming, Lin, Peter H., Yao, Qizhi, Chen, Changyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161135/
https://ncbi.nlm.nih.gov/pubmed/21571322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2011.03.018
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