Early Presymptomatic and Long-Term Changes of Rest Activity Cycles and Cognitive Behavior in a MPTP-Monkey Model of Parkinson's Disease

BACKGROUND: It is increasingly recognized that non-motor symptoms are a prominent feature of Parkinson's disease and in the case of cognitive deficits can precede onset of the characteristic motor symptoms. Here, we examine in 4 monkeys chronically treated with low doses of the neurotoxin MPTP...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Vezoli, Julien, Fifel, Karim, Leviel, Vincent, Dehay, Colette, Kennedy, Henry, Cooper, Howard M., Gronfier, Claude, Procyk, Emmanuel
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2011
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161087/
https://ncbi.nlm.nih.gov/pubmed/21887350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023952
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