Specificity and Actions of an Arylaspartate Inhibitor of Glutamate Transport at the Schaffer Collateral-CA1 Pyramidal Cell Synapse

In this study we characterized the pharmacological selectivity and physiological actions of a new arylaspartate glutamate transporter blocker, L-threo-ß-benzylaspartate (L-TBA). At concentrations up to 100 µM, L-TBA did not act as an AMPA receptor (AMPAR) or NMDA receptor (NMDAR) agonist or antagoni...

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Bibliographic Details
Main Authors: Sun, Weinan, Hoffman, Katie M., Holley, David C., Kavanaugh, Michael P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161057/
https://ncbi.nlm.nih.gov/pubmed/21887314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023765
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