Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons

BACKGROUND: Proanthocyanidin is a polyphenolic bioflavonoid with known antioxidant activity. Some flavonoids have a modulatory effect on [Ca(2+)](i). Although proanthocyanidin extract from blueberries reportedly affects Ca(2+ )buffering capacity, there are no reports on the effects of proanthocyanid...

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Hlavní autoři: Ahn, Seo-Hee, Kim, Hee Jung, Jeong, Imju, Hong, Yi Jae, Kim, Myung-Jun, Rhie, Duck-Joo, Jo, Yang-Hyeok, Hahn, Sang June, Yoon, Shin Hee
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160962/
https://ncbi.nlm.nih.gov/pubmed/21810275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-78
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