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Autophagy and innate immunity ally against bacterial invasion

In this feature of a paper recently published in Science from the Dikic laboratory, phosphorylation of the autophagy receptor optineuron by TBK1 leads to selective clearance of ubiquitin-coated cytosolic Salmonella enterica. The work thus implicates phosphorylation of autophagy receptors as a genera...

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Main Authors: Galluzzi, Lorenzo, Kepp, Oliver, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160664/
https://ncbi.nlm.nih.gov/pubmed/21785408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.244
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