Tdrd1 acts as a molecular scaffold for Piwi proteins and piRNA targets in zebrafish

Piwi proteins function in an RNAi-like pathway that silences transposons. Piwi-associated RNAs, also known as piRNAs, act as a guide to identify Piwi targets. The tudor domain-containing protein Tdrd1 has been linked to this pathway but its function has thus far remained unclear. We show that zebraf...

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Auteurs principaux: Huang, Hsin-Yi, Houwing, Saskia, Kaaij, Lucas J T, Meppelink, Amanda, Redl, Stefan, Gauci, Sharon, Vos, Harmjan, Draper, Bruce W, Moens, Cecilia B, Burgering, Boudewijn M, Ladurner, Peter, Krijgsveld, Jeroen, Berezikov, Eugene, Ketting, René F
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160653/
https://ncbi.nlm.nih.gov/pubmed/21743441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.228
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