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Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function

The mechanisms that govern receptor coalescence into functional clusters – often a critical step in their stimulation by ligand – are poorly understood. We used single-molecule tracking to investigate the dynamics of CD36, a clustering-responsive receptor that mediates oxidized LDL uptake by macroph...

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Main Authors: Jaqaman, Khuloud, Kuwata, Hirotaka, Touret, Nicolas, Collins, Richard, Trimble, William S., Danuser, Gaudenz, Grinstein, Sergio
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160624/
https://ncbi.nlm.nih.gov/pubmed/21854984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.06.049
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