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Dose- and Rate-Dependent Effects of Cocaine on Striatal Firing Related to Licking

To examine the role of striatal mechanisms in cocaine-induced stereotyped licking, we investigated the acute effects of cocaine on striatal neurons in awake, freely moving rats before and after cocaine administration (0, 5, 10, or 20 mg/kg). Stereotyped licking was induced only by the high dose. Rel...

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Detalhes bibliográficos
Main Authors: Tang, Chengke, Mittler, Taliah, Duke, Dawn C., Zhu, Yun, Pawlak, Anthony P., West, Mark O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160282/
https://ncbi.nlm.nih.gov/pubmed/17991811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.107.129734
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