Wird geladen...

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice

An imbalance between inhibitory and excitatory neurotransmission has been proposed to contribute to altered brain function in individuals with Down syndrome (DS). Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system and accordingly treatment with GABA...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Braudeau, J, Delatour, B, Duchon, A, Pereira, P Lopes, Dauphinot, L, de Chaumont, F, Olivo-Marin, J-C, Dodd, RH, Hérault, Y, Potier, M-C
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160204/
https://ncbi.nlm.nih.gov/pubmed/21693554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881111405366
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!