The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility

The cohesin complex is a ring-shaped proteinaceous structure that entraps the two sister chromatids after replication until the onset of anaphase when the ring is opened by proteolytic cleavage of its α-kleisin subunit (RAD21 at mitosis and REC8 at meiosis) by separase. RAD21L is a recently identifi...

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Detalhes bibliográficos
Main Authors: Herrán, Yurema, Gutiérrez-Caballero, Cristina, Sánchez-Martín, Manuel, Hernández, Teresa, Viera, Alberto, Barbero, José Luis, de Álava, Enrique, de Rooij, Dirk G, Suja, José Ángel, Llano, Elena, Pendás, Alberto M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160193/
https://ncbi.nlm.nih.gov/pubmed/21743440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.222
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