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Activation of Src and transformation by an RPTPα splice mutant found in human tumours
Receptor protein tyrosine phosphatase α (RPTPα)-mediated Src activation is required for survival of tested human colon and oestrogen receptor-negative breast cancer cell lines. To explore whether mutated RPTPα participates in human carcinogenesis, we sequenced RPTPα cDNAs from five types of human tu...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160186/ https://ncbi.nlm.nih.gov/pubmed/21725282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.212 |
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