The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins

The cytosolic chaperonin CCT is a 1-MDa protein-folding machine essential for eukaryotic life. The CCT interactome shows involvement in folding and assembly of a small range of proteins linked to essential cellular processes such as cytoskeleton assembly and cell-cycle regulation. CCT has a classic...

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Autori principali: Dekker, Carien, Roe, S Mark, McCormack, Elizabeth A, Beuron, Fabienne, Pearl, Laurence H, Willison, Keith R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160183/
https://ncbi.nlm.nih.gov/pubmed/21701561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.208
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