Opposing Roles of PARP-1 in MMP-9 and TIMP-2 expression and Mast Cell Degranulation in Dyslipidemic Dilated Cardiomyopathy

INTRODUCTION: Previously, we demonstrated that inhibition of poly(ADP-ribose) polymerase (PARP) exerts protective effects against high-fat (HF) diet-induced atherogenesis, in part, by increasing tissue inhibitor of metalloproteinase (TIMP)-2 expression. Given that characteristics of dilated cardiomy...

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Hlavní autoři: Hans, Chetan P., Feng, Yumei, Naura, Amarjit S., Troxclair, Dana, Zerfaoui, Mourad, Siddiqui, Danish, Jihang, Ju, Kim, Hogyoung, Kaye, Alan D., Matrougui, Khalid, Lazartigues, Eric, Boulares, A. Hamid
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159956/
https://ncbi.nlm.nih.gov/pubmed/20434371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carpath.2010.03.007
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