MPYS is required for IRF3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers c-di-AMP and c-di-GMP()

Cyclic-di-GMP and cyclic-di-AMP are second messengers produced by bacteria and influence bacterial cell survival, differentiation, colonization, biofilm formation, virulence, and bacteria-host interactions. Here, we show that in both RAW264.7 macrophage cells and primary bone-marrow–derived macropha...

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Bibliografiske detaljer
Main Authors:	Jin, Lei, Hill, Krista K., Filak, Holly, Mogan, Jennifer, Knowles, Heather, Zhang, Bicheng, Perraud, Anne-Laure, Cambier, John C., Lenz, Laurel L.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2011
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3159690/ https://ncbi.nlm.nih.gov/pubmed/21813776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100088
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MPYS is required for IRF3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers c-di-AMP and c-di-GMP()

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