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Visualization of UV-induced Replication Intermediates in E. coli using Two-dimensional Agarose-gel Analysis

Inaccurate replication in the presence of DNA damage is responsible for the majority of cellular rearrangements and mutagenesis observed in all cell types and is widely believed to be directly associated with the development of cancer in humans. DNA damage, such as that induced by UV irradiation, se...

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Главные авторы: Jeiranian, H. Arthur, Schalow, Brandy J., Courcelle, Justin
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159679/
https://ncbi.nlm.nih.gov/pubmed/21206470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2220
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