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Simultaneous quantification of buprenorphine, norbuprenorphine, buprenorphine glucuronide, and norbuprenorphine glucuronide in human placenta by liquid chromatography mass spectrometry

A LCMS method was developed and validated for the determination of buprenorphine (BUP), norbuprenorphine (NBUP), buprenorphine glucuronide (BUP-Gluc), and norbuprenorphine glucuronide (NBUP-Gluc) in placenta. Quantification was achieved by selected ion monitoring of m/z 468.4 (BUP), 414.3 (NBUP), 64...

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Detalhes bibliográficos
Main Authors: Concheiro-Guisan, Marta, Shakleya, Diaa M., Huestis, Marilyn A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159561/
https://ncbi.nlm.nih.gov/pubmed/19247639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-009-2706-z
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