NF-kappaB P50/P65 hetero-dimer mediates differential regulation of CD166/ALCAM expression via interaction with micoRNA-9 after serum deprivation, providing evidence for a novel negative auto-regulatory loop

CD166/ALCAM plays an important role in tumor aggression and progression as well as protecting cancer cells against apoptosis and autophagy. However, the mechanism by which pro-cell death signals control CD166 expression remains unclear. Here we show that following serum deprivation (SD), upregulatio...

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Bibliografische gegevens
Hoofdauteurs: Wang, Jiayi, Gu, Zhidong, Ni, Peihua, Qiao, Yongxia, Chen, Changqiang, Liu, Xiangfan, Lin, Jiafei, Chen, Ning, Fan, Qishi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2011
Onderwerpen:
Gene Regulation, Chromatin and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159468/
https://ncbi.nlm.nih.gov/pubmed/21572107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr302
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