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Conditional random pattern algorithm for LOH inference and segmentation
Motivation: Loss of heterozygosity (LOH) is one of the most important mechanisms in the tumor evolution. LOH can be detected from the genotypes of the tumor samples with or without paired normal samples. In paired sample cases, LOH detection for informative single nucleotide polymorphisms (SNPs) is...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Oxford University Press
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159432/ https://ncbi.nlm.nih.gov/pubmed/18974074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn561 |
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