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Glycan Shielding of the Influenza Virus Hemagglutinin Contributes to Immunopathology in Mice
Rationale: Pandemic influenza viruses historically have had few potential sites for N-linked glycosylation on the globular head of the hemagglutinin (HA) on emergence from the avian reservoir. Gain of glycans within antigenic sites of the HA during adaptation to the mammalian lung facilitates immune...
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Format: | Artigo |
Jezik: | Inglês |
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American Thoracic Society
2011
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159075/ https://ncbi.nlm.nih.gov/pubmed/20935106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201007-1184OC |
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