Thymic Stromal Lymphopoietin Gene Promoter Polymorphisms Are Associated with Susceptibility to Bronchial Asthma

Thymic stromal lymphopoietin (TSLP) triggers dendritic cell–mediated T helper (Th) 2 inflammatory responses. A single-nucleotide polymorphism (SNP), rs3806933, in the promoter region of the TSLP gene creates a binding site for the transcription factor activating protein (AP)–1. The variant enhances...

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Hauptverfasser: Harada, Michishige, Hirota, Tomomitsu, Jodo, Aya I., Hitomi, Yuki, Sakashita, Masafumi, Tsunoda, Tatsuhiko, Miyagawa, Takehiko, Doi, Satoru, Kameda, Makoto, Fujita, Kimie, Miyatake, Akihiko, Enomoto, Tadao, Noguchi, Emiko, Masuko, Hironori, Sakamoto, Tohru, Hizawa, Nobuyuki, Suzuki, Yoichi, Yoshihara, Shigemi, Adachi, Mitsuru, Ebisawa, Motohiro, Saito, Hirohisa, Matsumoto, Kenji, Nakajima, Toshiharu, Mathias, Rasika A., Rafaels, Nicholas, Barnes, Kathleen C., Himes, Blanca E., Duan, Qing Ling, Tantisira, Kelan G., Weiss, Scott T., Nakamura, Yusuke, Ziegler, Steven F., Tamari, Mayumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159073/
https://ncbi.nlm.nih.gov/pubmed/20656951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0418OC
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