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High-Sensitivity MALDI-MRM-MS Imaging of Moxifloxacin Distribution in Tuberculosis-Infected Rabbit Lungs and Granulomatous Lesions

MALDI-MSI is a powerful technology for localizing drug and metabolite distributions in biological tissues. To enhance our understanding of tuberculosis (TB) drug efficacy and how efficiently certain drugs reach their site of action, MALDI-MSI was applied to image the distribution of the second-line...

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Main Authors: Prideaux, Brendan, Dartois, Véronique, Staab, Dieter, Weiner, Danielle M., Goh, Anne, Via, Laura E., Barry, Clifton E., Stoeckli, Markus
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158846/
https://ncbi.nlm.nih.gov/pubmed/21332183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1029049
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