Identification of a Highly Conserved H1 Subtype-Specific Epitope with Diagnostic Potential in the Hemagglutinin Protein of Influenza A Virus

Subtype specificity of influenza A virus (IAV) is determined by its two surface glycoproteins, hemagglutinin (HA) and neuraminidase (NA). For HA, 16 distinct subtypes (H1–H16) exist, while nine exist for NA. The epidemic strains of H1N1 IAV change frequently and cause annual seasonal epidemics as we...

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Detalhes bibliográficos
Main Authors: Zhao, Rongmao, Cui, Shujuan, Guo, Li, Wu, Chao, Gonzalez, Richard, Paranhos-Baccalà, Gláucia, Vernet, Guy, Wang, Jianwei, Hung, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158760/
https://ncbi.nlm.nih.gov/pubmed/21886787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023374
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